The answer to this question depends on who YOU are. First we need to identify the source of your cramps. There are two main categories of muscle cramping; (1) cramping due to the state of your muscles, and (2) muscle cramping due to your nutrition. This two minute video from Dr. Jordan Metzl will help you understand the basics.
Endurolytes personally work for me. On really hot days I would take four tablets before my work out and then halfway through the bike I would take another four, and it seemed to do the trick during my training and most of my runs.
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